DEAD-box proteins can completely separate an RNA duplex using a single ATP
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چکیده
منابع مشابه
DEAD-box proteins can completely separate an RNA duplex using a single ATP.
DEAD-box proteins are ubiquitous in RNA metabolism and use ATP to mediate RNA conformational changes. These proteins have been suggested to use a fundamentally different mechanism from the related DNA and RNA helicases, generating local strand separation while remaining tethered through additional interactions with structured RNAs and RNA-protein (RNP) complexes. Here, we provide a critical tes...
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The RNA chaperone hypothesis suggests the existence of proteins that resolve misfolded RNA structures in vivo. A recent study has found an RNA-dependent ATPase that functions in this manner.
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متن کاملDEAD-box proteins
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2008
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0811075106